Fig. 2.
Specificity of phages isolated by selection on plasma-derived factor VIII light chain for the C2 domain.
Binding of phages to recombinant C2 domain that was immobilized via monoclonal antibodies CLB-CAg 117 or ESH4 was determined by enzyme-linked immunosorbent assay. The results were corrected for binding to both antibodies in the absence of C2 domain. Clones were divided into 2 groups, DP-5 and DP88, respectively, based on the variable heavy gene segment that encodes the VHdomain.