Fig. 4.
Effect of Ro 31-8220 on convulxin-induced platelet dense granule release.
Aspirin-treated and [3H]-serotonin loaded washed platelets were stimulated with varying concentrations of convulxin in the presence (shaded bars) or absence (open bars) of Ro 31-8220 (10 μM). The released [3H]-serotonin was measured as described in “Materials and methods.” Each data point is the mean ± SE of 3 measurements using different donors.