Pretreatment of platelets with MβCD dose-dependently inhibits collagen- or Cvx-induced platelet aggregation and ATP release.

Platelet aggregation and ATP release were studied as described in the legend to Figure 1. Inhibition of platelet aggregation and ATP release was calculated by comparing the maximal responses elicited by MβCD-treated platelets relative to those by untreated platelets. Data presented are mean ± SEM for 3 experiments.