Fig. 4.
Phosphorylated STAT5 (pSTAT5) as an indicator of γc signaling.
B-cell lines from a healthy control (panel A) and XSCID patients (panel B), before and after transduction. Cells were exposed (black line) or not exposed (dotted line) to IL-2, then permeabilized and stained with mouse anti-pSTAT5 and a FITC-conjugated anti–mouse secondary antibody.
