Expression of active caspase 3 and PARP-1/p89 in HD.

(A) Active caspase 3 expression in a patient with HD showing 5% or more active caspase 3–positive H/RS cells. (B) Expression of active caspase 3 in a patient with HD showing less than 5% active caspase 3–positive H/RS cells. (C) PARP-1/p89 expression in the same HD patient as depicted in Figure 5A, showing comparable numbers of PARP-1/p89 and active caspase 3–positive H/RS cells. (D) Expression of PARP-1/p89. The same HD patient depicted in Figure 5B, showing expression in a few small reactive but negative H/RS cells. Original magnification × 630.