Fig. 2.
Nonparametric analysis of the abnormal TCR-Vβ repertoire in AA patients.
Columns represent the mean numbers + SD of overexpressed Vβ-families of a total of 22 screened. Pathologic overrepresentation of a particular Vβ was defined as described in “Patients and methods.” Analysis of total αβ T cells is shown (A,B), whereas effector lymphocytes were analyzed (C,D). By analogy, analysis of αβ CD4+ (A,C) and αβ CD8+ (B,D) cells (in both total and effector [CD28dim] compartment) is depicted.