Preferential usage of Vβ families in AA patients prior to and after immunosuppressive therapy.

Two representative cases are shown, one for CD4⁺lymphocytes (A,B,E,F) and one for CD8⁺ lymphocytes (C,D,G,H); results in total cells (A,E,C,G) and effector pool (B,D,F,H) are depicted. Vβ usage prior to immunosuppressive treatment (B,F,D,H) is represented, whereas the corresponding results after therapy was administered (E,F,G,H) according to the regimen described in “Patients and methods” are shown.