American Society of Hematology

Fig. 5.

$Fig. 5. T-cell activation in the lymph nodes. / (A) Flow cytometric analysis of lymph nodes (mesenteric and inguinal) from 2 representative recipients of TβRII−/−and TβRII+/− bone marrow, respectively, at 8 weeks after transplantation. The samples were gated for FSC, SSC, Ly5.2, and CD4 or CD8, respectively. The percentages indicate the fraction of CD4+ or CD8+ cells that expresses CD69. Absolute numbers are shown in paranthesis (× 10−4). (B) Average fractions of CD4+ or CD8+ cells, respectively, expressing CD69. The numbers of animals examined were 6 (TβRII−/−recipients) and 3 (TβRII+/− recipients), respectively.P < .02 for CD4+ cells and < .001 for CD8+ cells. At least 10 000 counts were collected for each sample.$

T-cell activation in the lymph nodes.

(A) Flow cytometric analysis of lymph nodes (mesenteric and inguinal) from 2 representative recipients of TβRII^−/−and TβRII^+/− bone marrow, respectively, at 8 weeks after transplantation. The samples were gated for FSC, SSC, Ly5.2, and CD4 or CD8, respectively. The percentages indicate the fraction of CD4⁺ or CD8⁺ cells that expresses CD69. Absolute numbers are shown in paranthesis (× 10⁻⁴). (B) Average fractions of CD4+ or CD8+ cells, respectively, expressing CD69. The numbers of animals examined were 6 (TβRII^−/−recipients) and 3 (TβRII^+/− recipients), respectively.P < .02 for CD4⁺ cells and < .001 for CD8⁺ cells. At least 10 000 counts were collected for each sample.

This Feature Is Available To Subscribers Only