Fig. 2.
Fig. 2. Effect of VE-cadherin mAbs on formation of vascularlike structures by endothelial cells. / 1G11 cells were cultured in a tridimensional collagen gel. After 48 hours in the presence of nonimmune rat IgG (50 μg/mL), cells reorganized in a network of cordlike structures. In contrast, when exposed to equal concentrations of either mAb BV13 or BV14, the formation of the network was impaired. (Magnification × 100.)

Effect of VE-cadherin mAbs on formation of vascularlike structures by endothelial cells.

1G11 cells were cultured in a tridimensional collagen gel. After 48 hours in the presence of nonimmune rat IgG (50 μg/mL), cells reorganized in a network of cordlike structures. In contrast, when exposed to equal concentrations of either mAb BV13 or BV14, the formation of the network was impaired. (Magnification × 100.)

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