Fig. 4.
The kinetics of generation of CD8α
+CD11c−Lin−cell–derived splenic DCs. Each group of 4 irradiated Ly5.1 B6 mice was reconstituted with 5 × 105 sorted CD8α+CD11c−Lin− cells from the spleens of Ly5.2 B6 mice. Donor-derived DCs were identified as Ly5.2+Ia+ cells as described in Figure 3A at various time points (1 to 4 weeks) after transplantation. Each point is the mean ± 1 SD of 3 such reconstitution experiments, each based on a pool of 4 spleens from the reconstituted mice.
