Kinetics of appearance of BrdU-labeled granulocytes in circulation of wild-type and G-CSF–deficient mice.

The top (A) and the middle (B) panels show the proportion of granulocytes that are BrdU^bright and BrdU^dim in the blood of wild-type and G-CSF–deficient mice, respectively. The bottom panel (C) shows the number of BrdU-positive granulocytes in the blood of wild-type and G-CSF–deficient mice. The average time of appearance of BrdU^bright and BrdU^dimgranulocytes in wild-type and G-CSF–deficient mice is marked on the x-axes in panels (A) and (B). This is a representative plot of 3 independent experiments showing similar results. Data are represented as mean ± SEM (n = 3).