Transplantation regimen and posttransplantation course.

(A) A schematic representing the SCT regimen, and posttransplantation course, detailing GVHD, immunosuppression, disease status (by both cytogenetics and RT-PCR), and STI571 treatment. (B,C) Results of RT-PCR for RAB5EP-PDGFBR (R-P) and actin control transcripts. Pretransplantation bone marrow mRNA was diluted in negative control mRNA for semiquantitative purposes. In panel B, the patient's test samples are labeled by time from transplantation (12-18 months); in panel C the patient samples are labeled by time from initiating STI571 therapy (pre, immediately before initiating therapy). (D) Results of RT-PCR for RAB5EP-PDGFBR (R-P) and actin control transcripts, 6 months after initiation of STI571 therapy compared to pretransplantation and pre-STI571 time points.