Anandamide exposure leads to the induction of apoptosis in Molt-4 tumor cells in vitro.

Molt-4 tumor cells were cultured in serum-free medium in the presence or absence of various concentrations of anandamide (5, 10, 20, and 40 μM) or the vehicle for 4 hours. The induction of apoptosis was determined by the TUNEL method. A representative experiment in which Molt-4 tumor cells were cultured with anandamide (filled histogram) or the vehicle (open histogram) is depicted.