Dose dependence of inhibitory effect of BMSCs on T-lymphocyte proliferation.

T lymphocytes were cultured with allogeneic CD34⁺cell–derived DCs at 1:1 ratio without (white bars) BMSCs or in the presence of increasing numbers of BMSCs (black bars) from 1:0.2 to 1:5 ratios. The data are expressed as mean ± SD of triplicates of 3 separate experiments. *Statistically significant when compared with MLRs performed in the presence of BMSCs (Student t test for paired data).