Depletion of CD25⁺ cells from a whole T-cell inoculum accelerates GVHD in a nonirradiated SCID GVHD model.

The 10⁶ whole or CD25-depleted B6 T cells were infused into nonirradiated BALB/c SCID mice previously NK-depleted with antiasialo GM1. On the x-axis are days after transfer of cells. On the y-axis is the proportion of recipients surviving (n = 4/group;P = .021).