American Society of Hematology

Fig. 5.

$Fig. 5. Chimerism in LEW.1W rats treated with a high dose of anti-RT7a mAb and rescue by LEW.1W-7B BM transplantation. / LEW.1W rats (n = 4) received a high dose of anti-RT7a mAb (see above) on day 0. On day 1, 100 × 106 BM cells from LEW.1W-7B donors were transplanted. Leukocytes were obtained from whole blood samples and stained with respective mAbs (Figure 1). Patterns of chimerism are shown for T cells (panel A), B cells (panel B), and granulocytes (panel C). RT7a-positive recipient cells are shown as fractions of total T cells, B cells, and granulocytes as solid black boxes, whereas RT7b-positive donor cells are shown as gray boxes.$

Chimerism in LEW.1W rats treated with a high dose of anti-RT7^a mAb and rescue by LEW.1W-7B BM transplantation.

LEW.1W rats (n = 4) received a high dose of anti-RT7^a mAb (see above) on day 0. On day 1, 100 × 10⁶ BM cells from LEW.1W-7B donors were transplanted. Leukocytes were obtained from whole blood samples and stained with respective mAbs (Figure 1). Patterns of chimerism are shown for T cells (panel A), B cells (panel B), and granulocytes (panel C). RT7^a-positive recipient cells are shown as fractions of total T cells, B cells, and granulocytes as solid black boxes, whereas RT7^b-positive donor cells are shown as gray boxes.

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