Fig. 1.
Inhibition of anti-HLA F(ab′)2 fragments.
Ability of intact IgG derived from commercial IVIg (○), sera from men (■), or sera from multiparous women (●), to inhibit reactivity of anti-HLA F(ab′)2 fragments. Anti-HLA reactivity is expressed as median channel fluorescence (mean ± SD, n = 6) at the indicated intact IgG/anti-HLA F(ab′)2molar ratios. As controls, the anti-HLA reactivity of the 3 intact IgG preparations (x-axis = C) and of anti-HLA F(ab′)2fragments (x-axis = 0, ▵) incubated only with phosphate-buffered saline is shown. The stars indicate significance (★:P < .05, ★★: P < .01) between data points for intact IgG from multiparous women versus intact IgG derived from commercial IVIg.
