Fig. 4.
Anti-HLA alloimmune response in SCID mice.
Development of human anti-HLA alloimmune response in SCID mice (n = 93) engrafted with PBMCs from an alloimmunized donor and challenged twice weekly for 4 weeks with allogeneic PBMCs. Data are expressed as the median channel fluorescence (mean ± SD) of SCID mouse sera at a 1:100 dilution.