Fig. 3.
Stimulation with nucleotides induces actin polymerization in immature but not mature DCs.
(A) Nucleotide dose-dependency of f-actin polymerization in immature DCs. (B) Nucleotide dose-dependency of f-actin polymerization in mature DCs. (C) Time course of f-actin polymerization in immature DCs (nucleotide concentration was 10−4 M; C5a was 10−8 M). (D) Time course of f-actin polymerization in mature DCs (nucleotide concentration was 10−4 M; MIP-3β was 10−8 M). The relative f-actin content was determined at the indicated time points by flow cytometry. Data are expressed as mean ± SEM (n = 4).