Increased apoptosis in MDS as measured by mitochondrial potential.

(A) Representative example of mitochondrial potential analysis showing greater apoptotic activity in bone marrow of a patient with MDS (green, detected on FL2, instead of orange, detected on FL1) than in that of a patient with AML. (B) Box plot showing overall significantly higher apoptotic activity (disturbance in mitochondrial potential) in patients with MDS than in those with AML. (C) Box blot showing significantly greater percentage of cells with disturbance in mitochondrial potential from patients with various subtypes of MDS than in those from patients with AML. (D) Box blot showing significantly greater percentage of polymorphonuclear cells with disturbance in mitochondrial potential from patients with various subtypes of MDS than in those from patients with AML.