Increased proliferation in MDS.

(A) Representative example demonstrating greater BrdU incorporation in CD34⁺cells of a patient with MDS than in those of a patient with AML. (B) Box plot showing significantly greater BrdU incorporation in cells of patients with MDS than in those of patients with AML. (C) Box plot showing significantly greater BrdU incorporation in CD34⁺cells of patients with various subtypes of MDS than in those of patients with AML. The number of patients in the RAEB-T group is small (4 patients), and the apparent increase in BrdU incorporation in this group may not be accurate.