Reconstitution of CMV-specific T-cell responses and viral load after T-cell transfer.

In patient no. 4, after a high viral load at the time of T-cell transfer, already on day +15 viral load decreased to 800 viral copies/mL blood. At day 38, when the virus had been cleared entirely, reconstitution of CMV-specific lymphoproliferation and CMV peptide-specific A*0201-restricted CD8⁺ T cells was also shown by intracellular IFN-γ and tetramer staining.