Fig. 3.
AYPGKF-induced inhibition of adenylyl cyclase in P2Y12-deficient mouse platelets.
Effect of varying concentrations of AYPGKF on PGE1-stimulated cAMP levels in platelets from mice deficient in the P2Y12 receptor were determined and compared with wild-type mouse platelets. The data are derived from at least 3 independent experiments. Each data point is the mean ± SE of 3 experiments. *P < .05 by Student t test when compared with the value of PGE1.