Fig. 4.
DNA enzyme–mediated catabolism of mRNA–Raf-1 in JMML cells.
The active, but not the inactive, DNA enzyme (1 μg/mL) reduced mRNA–Raf-1 in JMML cells. The control mRNA-GAPDH did not change appreciably upon enzyme treatment. The results were obtained from RNAse protection assays and are from one experiment on one JMML case and representative of 7 other JMML cases.