DNA enzyme treatment abolished GM-CSF hypersensitivity in JMML cells.

Whereas JMML cells showed hypersensitivity to GM-CSF (A), this could not be detected for either TNF-α (B) or G-CSF (C). The values (mean ± SEM, n = 3) are shown as dose-response curves based on colony scores from one JMML case and are representative of 7 other JMML cases.