Fig. 7.
Dose response curves.
Dose-response curves for the HD adenovirus AdFTC/hFIX (A) and the first-generation adenovirus fgAdhFIX (B). Mice were injected with varying doses of adenovirus ranging from 1 × 109transducing particles to 1 × 106 transducing particles. ♦ = 1 × 109 transducing particles; ⋄ = 5 × 108 transducing particles; ■ = 1 × 108 transducing particles; ▵ = 5 × 107 transducing particles; ▴ = 1 × 107 transducing particles; ○ = 5 × 106 transducing particles; ● = 1 × 106 transducing particles. Mean ± SD is shown (n = 3 per group).