Survival of B10.MBR and B10.BR skin grafts on recipients reconstituted with either VSV-Kb– or mock-transduced BM.

Survival of B10.MBR (closed symbols) and third-party B10.BR (open symbols) skin grafts on mice receiving VSV-Kb–transduced BM (squares) or mock-transduced BM (triangles). Survival of B10.MBR skin grafts was significantly prolonged on mice receiving VSV-Kb–transduced BM (MST = 98 days, n = 18) when compared to survival on controls receiving mock-transduced BM (MST = 15 days, n = 14,P = .0001 between groups). No difference was observed in survival of third-party B10.BR skin on mice receiving VSV-Kb– or mock-transduced BM (MST = 14 and 15 days, respectively;P = .3). Shown are the combined the results of 2 independent experiments.