Fig. 2.
Effect of oxidized EPA on rolling and adhesion of neutrophils under laminar flow.
HUVECs were treated with vehicle alone or native or oxidized EPA (100 μM) for 1 hour prior to stimulation with LPS for 5 hours. The HUVEC-containing coverslip was placed in a parallel plate flow chamber and resting neutrophils (106/mL) were infused at 0.5 dynes/cm2 wall shear stress. The number of rolling (A) and adherent neutrophils (B) were determined and averaged ± SEM. *P < .00007 compared with Veh + LPS, n = 3.
