Videotaped images of the inhibition of cytoadherence by PpMC-179 on TNF-α–stimulated human microvasculature in vivo.

Panel A shows rolling and adherent IRBCs as distinct bright circles in the postcapillary venules. Panel B shows the same vessel 30 seconds later, with the arrows indicating adherent IRBCs. Panels C and D, show the appearance of postcapillary venules when IRBCs were injected 10 to 15 minutes after 2 μm PpMC-179. The IRBCs were no longer adherent and were either rolling or became completely noninteracting (streaks).