Fig. 4.
Correlation analysis of GFP+ human lymphoid and GFP+ human myeloid cells in individual recipients of transduced human fetal liver cells.
Left panel: The number of GFP+ human CD19/20+B-lymphoid cells per mouse is plotted as a function of the number of GFP+ human CD15+granulopoietic cell numbers in the same mice for 15 NOD/SCID (●) and 16 NOD/SCID-β2m−/− mice (○). A similar plot is shown on the right for GFP+ human CD19/20+B-lymphoid cells numbers as a function of GFP+ human glycophorin A+ erythroid cells in the same mice. Values shown were calculated assuming that the content of 2 tibias and 2 femurs represents 25% of the total marrow mass of a mouse.34 The correlation coefficients for each set of data are shown in the top left corner of the corresponding panel.