Fig. 3.
Responsiveness of CD18 to RA following integration into chromatin.
U937 cells were stably transfected with the indicated CD18 promoter constructs. Individual colonies were isolated, and equal aliquots of cells were treated with 10−5 M RA or DMSO (0.1%). Luciferase activity was measured 24 hours later; fold induction represents the relative activity of the RA-treated sample divided by the paired DMSO control sample. All data represent the mean and standard error of at least 3 independent clones, each tested in at least triplicate.
