Fig. 1.
Microarray data.
(A) Comparative analysis of microarray data of HS-27a and HS-5 cell lines. Gene sequences that were determined to have significantly different (P < .05) levels of expression in HS-27a cells compared to HS-5 cells are represented by a dot. Gene expression levels in HS-27a cells are shown on the x-axis. The y-axis indicates gene expression of HS-27a divided by HS-5. Therefore, genes expressed highly in HS-27a compared to the Universal control are at the far right in both the upper and lower quadrants. Genes that are also expressed to a greater degree in HS-27a compared to HS-5 are in the upper right quadrant. Two open circles in the upper right quadrant designate IL-7R. The dotted line indicates 10-fold higher gene expression for HS-27a than HS-5. (B) Microarray data on cytokine receptors in HS-27a and HS-5. Gene expression of 22 cytokine receptors from HS-27a (solid bars) and HS-5 (open bars) is shown as the ratio of hybridization signal from each stromal cell line to the hybridization signal from the Universal control RNA. Each bar represents the average ± SD for 4 samples. Stars indicate cytokine receptors whose gene expression is statistically different between HS-27a and HS-5 (*P < .05, **P < .005, and ***P < .0001).