Overall relationship between estimate of myocardial iron concentration and indices of iron status in 14 patients with transfusional iron overload during iron chelation. Myocardial iron estimates are obtained from Figure 4. The relationship between the myocardial iron estimates and the urinary iron excretion, the liver iron concentration, and the serum ferritin concentration was investigated by lowess regression analysis (tension 66). Panels A and E are based on 99 MRI examinations (5-10 examinations in each patient), and panels B-D on 76 examinations (no follow-up of urinary iron in patients 7, 12, and 14).