Figure 7.
Figure 7. Cotransferred congenic (Thy-1.1) cells do not inhibit the emergence of host-derived (Thy-1.2) cells in TCR–/– → F1 mice. To determine the influence of mature peripheral T cells on T-cell reconstitution by host cells, bone marrow chimeras were prepared in which 20 × 106 Thy-1.1+ T cells were cotransferred with either B6.Thy-1.2 BM or TCR—/—.Thy-1.2 BM into lethally irradiated B6.Thy-1.2 recipients. Staining profiles of lymph node and spleens of one mouse from each group as well as control mice are shown. Samples were stained with FITC-J1j (anti-Thy-1.2) and FITC-T11De (anti-Thy-1.1).

Cotransferred congenic (Thy-1.1) cells do not inhibit the emergence of host-derived (Thy-1.2) cells in TCR–/– → F1 mice. To determine the influence of mature peripheral T cells on T-cell reconstitution by host cells, bone marrow chimeras were prepared in which 20 × 106 Thy-1.1+ T cells were cotransferred with either B6.Thy-1.2 BM or TCR—/—.Thy-1.2 BM into lethally irradiated B6.Thy-1.2 recipients. Staining profiles of lymph node and spleens of one mouse from each group as well as control mice are shown. Samples were stained with FITC-J1j (anti-Thy-1.2) and FITC-T11De (anti-Thy-1.1).

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