Figure 2.
A comparison of the most frequently used VH genes in CD5+IgM+ normal B cells with mantle cell lymphoma VH genes. Data on frequency of VH gene use in normal B cells from Brezinschek et al.32 n indicates normal B cells; MCL, mantle cell lymphoma cases; U, unmutated IgVH genes (≥ 98% germ-line homology); and M, mutated IgVH genes (< 98% homology).