Development of thymocytes from VEGF-treated and tumor-bearing mice. (A) Schematic representation of T-cell development in the thymus. (B) Mice treated with VEGF as described in Figure 1 were killed and thymocytes analyzed for expression of CD4 and CD8 within a gated CD3^–/low population. Representative FACS plots are shown. (C) Percentage of thymocyte subsets in mice infused with VEGF (mean ± SE; N > 3). (D) Absolute number of thymocytes within TN subsets (mean ± SE; N > 3). *Denotes statistical significance.