Figure 7.
EPO expression in serum and the ratio of erythroid to myeloid precursors in bone marrow. (A) Western blot analysis of EPO in serum. Serum was collected at the indicated times from the peripheral blood of Prx II+/+ and Prx II–/– mice. Each fraction was separated by 12% SDS-PAGE and Western blot hybridized with antierythropoietin antibody. “W” and “H” indicate samples from the wild-type and Prx II–/– mice, respectively. (B-C) Bone marrow smears in wild-type (B) and Prx II–/– mice (C). Dark black cells indicate normoblasts. Original magnification, × 1000.