Figure 1.
Kinetics of WBC and CFU-C peripheralization in mice treated with a single injection of Ptx, B-oligomer, or cholera toxin on day 0. Only the Ptx holotoxin (solid lines), but not B-oligomer (dotted lines), mobilizes CFU-Cs (B) and increases WBCs (A), whereas cholera toxin (dashed lines) causes a prolonged depression of both WBCs (C) and CFU-Cs (D). The inset in panel B depicts CFU-S/mL blood in control (dark bar) and in Ptx-treated (white bar) animals. Horizontal gray lines in panels A-D represent mean control levels.