MYH9 localization in megakaryocytes. Immunofluorescence micrographs of the bone marrow from a healthy donor (A-B) and the patient with the Asp1424Asn mutation (C-D). Shown are 2 megakaryocytes with a typical staining of their cytoskeleton with MYH9/MYH10 antibodies in one of the 5 donors studied and the patient, respectively. Rhodamine staining. Original magnification × 1000 for all panels.