Liver histopathology after MCMV infection. (A) Severe MCMV hepatitis day 20 following LT-HSC transplantation (original magnification × 40). (B) Lymphocytic infiltration day 20 following CLP cotransplantation (original magnification × 40). Panels A and B are stained with H&E. Arrows indicate cytomegalic hepatocytes with viral inclusions. (C-D) Immunofluorescent localization of lacZ-tagged MCMV RM427⁺ (green; original magnification × 10) in mice that received LT-HSCs (C) and CLP cotransplants (D). (E) Immunohistochemical detection of CD45.1⁺ CLP-derived cells in the liver (brown, counterstained with hematoxylin).