Host cells contribute to control of MCMV infection. (A) Survival of mice that received transplants with (▾, ▿) or without (•, ○) depletion of Thy1.2⁺ host cells. Survival of mice that received transplants of 500 LT-HSCs (•; n = 9, 55.6% survival) or 500 LT-HSCs and 3000 CLPs (○; n = 10, 80% survival) compared with mice that received transplants of 500 LT-HSCs (▾; n = 10, 0% survival) or 500 LT-HSCs and 3000 CLPs (▿; n = 9, 33.3% survival) with subsequent Thy1.2 depletion. P = .03 (• versus ▾), P = .04 (▿ versus ▾). (B) Splenic FACS analysis on day 35 of infected survivors that received CLP cotransplants confirmed complete depletion. Thy 1.1⁺ cells are LT-HSC and CLP derived, the majority again was CLP derived (also shown in Figure 7B).