American Society of Hematology

Figure 2.

$Figure 2. Turbidity generation from thrombin-treated γA/γA, γA/γ′ and unfractionated fibrinogen. Unfractionated (thin line), γA/γA (normal weight line) and γA/γ′ (thick line) fibrinogen was incubated at 1 mg/mL with 0.5 (A), 1 (B), and 2 (C) IU/mL human α thrombin and 10 mM calcium. Generation of turbidity at 350 nm was measured every 10 seconds for 4 minutes. Fibrinogen γA/γ′ demonstrated altered polymerization rates.$

Turbidity generation from thrombin-treated γA/γA, γA/γ′ and unfractionated fibrinogen. Unfractionated (thin line), γA/γA (normal weight line) and γA/γ′ (thick line) fibrinogen was incubated at 1 mg/mL with 0.5 (A), 1 (B), and 2 (C) IU/mL human α thrombin and 10 mM calcium. Generation of turbidity at 350 nm was measured every 10 seconds for 4 minutes. Fibrinogen γA/γ′ demonstrated altered polymerization rates.

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