Figure 2.
Histologic analysis of [II–/– → wt] chimeric mice reveals systemic GVHD. Histologic analysis of [II–/– → wt] chimeras 10 weeks after BMT showed periportal mononuclear infiltrates (A) and endothelialitis (B, arrow) in liver, dermal mononuclear infiltrates in the skin (C), and crypt cell apoptosis in the small intestine (D, arrow). Original magnification × 200 (A, C, D) and × 400 (B).