Figure 4.
Thymectomy of BM transplant recipients prevents the development of GVHD. (A-C) Wt mice were thymectomized (Tx) and received transplants of TCD BM from II–/– donors following 13 Gy TBI. Survival (A) and clinical GVHD scores (B) are shown after BMT (n = 5-9/group). (C) Pathology scores of the liver and intestine at 7 weeks after BMT (n = 3/group). Mean ± SE is shown. *P < .01, **P < .05.