Different TCR usage between HLA-E tetramer–positive T cells and immunodominant Tax11-19–specific CD8⁺ T cells from HTLV-1–infected individuals. (A) CDR3 length profiles for TCR transcripts in CD8⁺ HLA-E tetramer–positive (top row) and HLA-A^*02/Tax11-19 tetramer–positive (bottom row) T cells were examined for 4 HLA-A^*02⁺ HAM/TSP patients. A representative result from one HLA-A^*02⁺ HAM/TSP patient is shown. (B) Two-color flow cytometric analysis using HLA-A^*02/Tax11-19 tetramer and anti-NKG2A mAb from HLA-A^*02⁺ HAM/TSP patients. Four HLA-A^*02⁺ HAM/TSP patients were examined. A representative result from one HLA-A^*02⁺ HAM/TSP patient is shown.