Figure 2.
Platelet aggregation responses to various kinds of agonists. PRPs (3 × 105/μL) were incubated at 37°C for 10 minutes prior to stimulation. Changes to morphology and aggregation of platelets from wild-type (WT, left column) and p85α–/– (right column) were measured using an aggregometer after stimulation with collagen, CRP, ADP, U46619, thrombin, PMA, A23187, and botrocetin at the indicated concentrations. Bars indicate 1 minute. Results are from 1 experiment but are representative of at least 4 separate experiments.
