Purging effect of reovirus on U937 monocytic cells and RPMI 8226 myeloma cells. Admixtures of apheresis product cells and U937 monocytic cells (Ai,Bi,Ci) or RPMI 8226 cells (Aii,Bii,Cii) (1%, 0.1%, and 0.01%, respectively) were treated with reovirus (40 MOI). Following 3 days of purging, CD33⁺/CD45⁺ U937 cells or CD138⁺/CD38⁺ myeloma cells were assessed by flow cytometry. (A) Flow cytometric plots of purged and unpurged samples. (B) U937 and RPMI 8226 cell numbers in purged and unpurged samples. Arrows indicate the absence of live cells. (C) Lack of out growth of U937 (i) and RPMI 8226 cells (ii) in purged samples following 6 days of incubation. Arrows indicate the absence of regrowth of U937 or RPMI 8226 cells. Error bars represent the standard deviations of the means of 3 replicates.