Figure 3.
Differentially expressed genes after BMT. Recipient mice underwent transplantation and their livers were harvested on days 7 and 35 after BMT as described above. Total RNA was isolated from the harvested liver samples, and microarray analysis was performed using the mouse genome U74A Ver.1 Arrays oligonucleotide microarrays as described in “ Materials and methods. ” Allogeneic and syngeneic BMT samples were compared for the expression level of each gene at either day 7 or day 35. Those genes demonstrating the largest transcriptional alterations, a 3.5-fold change (FC) or greater, are shown (*P < .01).