Invasive fungal infections and GVHD. Cumulative incidence rates of invasive mold infections among 105 nonmyeloablative transplant recipients who developed acute GVHD (A) and cumulative incidence rates of invasive fungal infections among 118 nonmyeloablative transplant recipients who were treated with corticosteroids for GVHD (B). Patients who developed invasive fungal infections before the onset of acute GVHD or before beginning corticosteroid therapy were not included in these graphs. The 1-year cumulative incidence rates of invasive mold infection (IMI) were 42% in patients with grades III to IV GVHD (n = 24; solid line) and 14% in patients with grades I to II GVHD (n = 81; dotted line). The 6-month cumulative incidence rates of invasive fungal infections (IFI; solid line), invasive mold infections (dashed line), and invasive candidiasis (dotted line) after beginning corticosteroid therapy (≥ 1 mg/kg/d prednisolone equivalents) were 23%, 18%, and 6%, respectively. Ticks on probability lines indicate dates of censoring at last follow-up.