Figure 2.
Human CD3+cells in PB of NOD/SCID/γcnull, NOD/SCID-β2mnull, and NOD/SCID mice that underwent transplantation with CB CD34+cells. (A) Percentage of human CD3+cells among human CD45+cells in PB was analyzed sequentially after the transplantation of 4 × 104 CB CD34+cells. Results of 2 independent experiments (n = 3 each) are shown. Error bars represent SDs. (B) Surface phenotypes of human CD3+T cells in thymus, spleen, and BM of NOD/SCID/γcnull mice were evaluated 5 months after the transplantation of 2 to 4 × 104 CB CD34+cells. Representative data from 5 independent analyses of similar results are shown.